When people think of cannabis, two compounds usually come to their mind: THC and CBD, the non-intoxicating cannabinoid known for its therapeutic benefits. However, cannabis contains over 100 different cannabinoids, many of which remain understudied but show promising effects.
In this blog, we’ll explore some of these lesser-known cannabinoids, their potential benefits, and how they might shape the future of cannabis medicine and wellness.
What are Cannabis & Cannabinoids?
Cannabis is a plant that has been used for medicinal, recreational, and industrial purposes for centuries. It is also known as marijuana, pot, weed, etc. It contains a variety of compounds, including cannabinoids, terpenes, and flavonoids, which contribute to its effects.
On the other hand, cannabinoids are the active compounds in cannabis that interact with the endocannabinoid system (ECS) in the human body, influencing mood, pain, appetite, and other physiological functions.
The well-known cannabinoids are THC & CBD, where THC has psychoactive effects that make you “high”. And CBD doesn’t make you “high” but has therapeutic effects that provide you a lot of medical benefits.
What are Lesser-Known Cannabinoids?
Lesser-known cannabinoids are naturally occurring compounds in cannabis. But they have smaller concentrations compared to THC and CBD. Although they are not as widely studied, early research suggests they also offer unique therapeutic benefits.
These compounds interact with the body’s endocannabinoid system and influence human functions such as pain relief, mood regulation, and inflammation.
Minor Cannabinoids & Their Effects?
1. CBG (Cannabigerol) – The “Mother of Cannabinoids”
CBG is the precursor to THC, CBD, and other cannabinoids, earning it the nickname “the stem cell of cannabis.” Potential benefits:
- Anti-inflammatory – May help with conditions like IBS and Crohn’s disease.
- Neuroprotective – Shows promise in treating neurodegenerative diseases like Huntington’s.
- Antibacterial – Effective against drug-resistant bacteria like MRSA.
2. CBN (Cannabinol) – The Sleep Aid?
Formed when THC breaks down over time (commonly found in aged cannabis). Potential benefits:
- Sedative effects – Often marketed as a natural sleep aid.
- Pain relief – May help with chronic pain and inflammation.
- Appetite stimulation – Could benefit those with appetite loss.
3. CBC (Cannabichromene) – The Mood Booster
A non-psychoactive cannabinoid that interacts with receptors beyond the ECS. Potential benefits:
- Antidepressant – May boost mood by increasing anandamide (the “bliss molecule”).
- Anti-inflammatory – Could help with conditions like arthritis.
- Neurogenesis – Might promote brain cell growth.
4. THCV (Tetrahydrocannabivarin) – The Weight Manager
What it is – structurally similar to THC but with different effects. Potential benefits:
- Appetite suppressant – Unlike THC, it may reduce hunger.
- Blood sugar regulation – Being studied for diabetes management.
- Anticonvulsant – Could help with epilepsy.
5. CBDV (Cannabidivarin) – The Seizure Fighter
A cousin of CBD, often found in landrace cannabis strains. Potential benefits:
- Anti-seizure – Research suggests potential for epilepsy treatment.
- Anti-nausea – May help with chemotherapy-induced nausea.
- Autism research – Early studies explore its effects on autism-related symptoms.
How These Cannabinoids Work Together?
Cannabinoids do not work in isolation; instead, they contribute to what is known as the “entourage effect.” This concept suggests that cannabinoids, terpenes, and other compounds in cannabis work synergistically and enhance their therapeutic effects in cannabis.
By combining multiple cannabinoids, users may experience improved benefits compared to using a single isolated compound. But remember to consult a cannabis expert and take their suggestion to make cannabis strains to have e better experience with the most benefits.
How are These Cannabinoids Extracted & Consumed?
Since minor cannabinoids appear in low concentrations, so extracting them is challenging. However, advances in selective breeding and extraction techniques have made it possible to isolate them. Let’s learn some methods:
- CO2 Extraction: Uses pressurized CO2 for pure, high-quality extracts, preserving cannabinoids’ potency.
- Solvent Extraction: Uses ethanol or butane to dissolve cannabinoids, though it requires purification to remove solvents.
- Oil Extraction: Uses oils like coconut or olive oil, commonly for small batches.
- Distillation: Separates cannabinoids through heat, producing highly concentrated extracts.
After extracting these cannabinoids, it is marketed as available products like oils and edibles.
Future of Minor Cannabinoids in Research
Research on minor cannabinoids is still in its early stages, but interest is rapidly growing. Scientists and medical professionals are exploring their potential applications in treating conditions such as chronic pain, anxiety, epilepsy, and more.
Additionally, as cannabis legalization expands, new products featuring minor cannabinoids are emerging, offering consumers more targeted therapeutic options.
Some recent findings are:
- CBG could become a treatment for glaucoma and inflammatory bowel disease.
- THCV might be used in diabetes and obesity management.
- CBC and CBDV could play roles in mental health and neurological disorders.
Wrap-Up
Exploring beyond THC and CBD opens the door to powerful, lesser-known cannabinoids with unique benefits. Whether you prefer vaping, tinctures, edibles, or topicals, there’s a perfect way to experience their effects.
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Reach out now and start your journey to better wellness!
